SCHEMBL4451236

SCHEMBL4451236

CC(C)(C)c1ccc(O)c(-n2nnc3ccccc32)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 2/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 2/20 0.40
POLB P06746 2/20 0.39
MAPK1 P28482 1/20 0.39
SLC9A1 P19634 1/20 0.39
KEAP1 Q14145 1/20 0.39
RECQL P46063 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11521392 0.89 KCNMA1 (0.61) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL9437945 0.88 KCNMA1 (0.57) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL2595377 0.86 KCNMA1 (0.55) KCNMA1SMN1; SMN2TSHRHSD17B10KMT2A
SCHEMBL29576845 0.86 KCNMA1 (0.55) KCNMA1SMN1; SMN2TSHRHSD17B10KMT2A
SCHEMBL22797091 0.84 KCNMA1 (0.51) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL29845601 0.81 KCNMA1 (0.67) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL890612 0.81 KCNMA1 (0.67) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL4963816 0.81 KCNMA1 (0.51) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL11880576 0.81 KCNMA1 (0.71) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1
SCHEMBL28463764 0.80 KCNMA1 (0.50) KCNMA1SMN1; SMN2TSHRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020203869-A1 METHOD FOR PRODUCING OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL 三井化学株式会社 2020-10-08 WO disclosed
US-7550541-B2 Resin composition and molded article, film and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2009-06-23 US disclosed
US-20070260019-A1 Resin composition and molded article, film and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2007-11-08 US disclosed
US-7268190-B2 Resin composition comprising polylactic acid and polyacetal and a molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2007-09-11 US disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
US-20040171867-A1 Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition OKAZAKI AKIRA (JP) 2004-09-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-6767987-B2 CURABLE RESIN COMPOSITION COMPRISING ACRYLIC POLYOL RESIN INCLUDING HYDROXYALKYL(METH)ACRYLATE COMPOSITION HAVING SMALL AMOUNT OF POLYMERIZED LACTONE MONOMER, AND MELAMINE RESIN DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-07-27 US disclosed
US-20030149227-A1 Lowly lactone-modified reactive monomer composition, acrylic polyol resins produced with the same, curable resin compositions and coating compositions DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-08-07 US disclosed
EP-1227113-A1 LOWLY LACTONE-MODIFIED REACTIVE MONOMER COMPOSITION, ACRYLIC POLYOL RESINS PRODUCED WITH THE SAME, CURABLE RESIN COMPOSITIONS AND COATING COMPOSITIONS DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2002-07-31 EP disclosed
US-4368258-A HYDROPHOBIC SUBSTANCE, WATER-MISCIBLE SOLVENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-01-11 US disclosed
US-4246333-A FOR COLOR DIFFUSION TRANSFER PROCESS ALLOWING A RANGE OF PROCESSING TEMPERATURES; A CYANOETHYL HETEROCYCLIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-01-20 US disclosed
US-4232118-A METHINECYANINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-11-04 US disclosed
US-3960570-A ALPHA-ACYLACETOAMIDE YELLOW DYE FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171867-A1 Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition MSR1, FUT4, MRE11 KCNMA1 3017/4885SMN1; SMN2 814/4885TSHR 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.