SCHEMBL890612

SCHEMBL890612

Cc1ccc(O)c(-n2nnc3ccccc32)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 2/20 0.67
RAB9A P51151 4/20 0.56
LMNA P02545 2/20 0.56
NPC1 O15118 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.47
TSHR P16473 1/20 0.47
GAA P10253 4/20 0.46
ALDH1A1 P00352 1/20 0.46
MGAM O43451 2/20 0.45
AMY1A P0DUB6 2/20 0.45
SI P14410 2/20 0.45
MGAM2 Q2M2H8 2/20 0.45
KMT2A Q03164 2/20 0.42
MAPK1 P28482 2/20 0.42
SLC9A1 P19634 2/20 0.42
POLB P06746 2/20 0.42
ATM Q13315 1/20 0.42
KEAP1 Q14145 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845601 1.00 KCNMA1 (0.67) KCNMA1RAB9ALMNANPC1SMN1; SMN2
SCHEMBL8645601 0.88 KCNMA1 (0.67) KCNMA1RAB9ALMNANPC1SMN1; SMN2
SCHEMBL13772814 0.84 KCNMA1 (0.57) KCNMA1RAB9ALMNASMN1; SMN2TSHR
SCHEMBL11880576 0.84 KCNMA1 (0.71) KCNMA1RAB9ALMNASMN1; SMN2TSHR
Phenyl Salicylate SCHEMBL29221501 0.82 KCNMA1 (0.49) KCNMA1RAB9ALMNANPC1SMN1; SMN2
SCHEMBL24222175 0.82 KCNMA1 (0.50) KCNMA1RAB9ALMNASMN1; SMN2TSHR
SCHEMBL502853 0.82 KCNMA1 (0.67) KCNMA1RAB9ANPC1SMN1; SMN2TSHR
SCHEMBL11612145 0.82 KCNMA1 (0.67) KCNMA1RAB9ALMNANPC1SMN1; SMN2
SCHEMBL25874452 0.82 KCNMA1 (0.50) KCNMA1RAB9ALMNASMN1; SMN2TSHR
SCHEMBL25873809 0.82 KCNMA1 (0.50) KCNMA1RAB9ALMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027882-A1 Sunscreening compositions containing a benzotriazole derivative and a compound containing benzoazolyle or benzodiazolyle groups L'OREAL (FR) 2000-08-16 EP claimed
US-6014998-A HAVING IMPROVED CURE RATE AND DYNAMIC MODULUS; MIXING ONE TRIAZOLE, SILICA AND COUPLING AGENT; TIRE RUBBER COMPONENTS PIRELLI PNEUMATICI S.P.A. (IT) 2000-01-18 US claimed
EP-0964028-A1 Silica reinforced tire compositions containing triazoles Pirelli Pneumatici S.p.A. (IT) 1999-12-15 EP claimed
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP claimed
US-5522921-A Invisible, x-ray opaque fluorescent printing medium for multiplex reading CUSTER PETER (US) 1996-06-04 US claimed
US-5508339-A Acrylic/lactam resin compositions and method of producing same QUEST TECHNOLOGIES, INC. 1996-04-16 US claimed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US claimed
JP-60222803-A None JP disclosed
JP-63086753-A None JP disclosed
US-20250361349-A1 MONOMER MIXTURE FOR PRODUCING A DENTAL MATERIAL MUEHLBAUER TECH GMBH (DE) 2025-11-27 US disclosed
US-12318459-B2 Thermoactive dental composite composition VOCO GMBH (DE) 2025-06-03 US disclosed
EP-4551180-A1 MONOMER MIXTURE FOR PRODUCING A DENTAL MATERIAL Mühlbauer Technology GmbH (DE) 2025-05-14 EP disclosed
US-12186416-B2 Monomer mixture for producing a dental material MÜHLBAUER TECHNOLOGY GMBH (DE) 2025-01-07 US disclosed
EP-0020612-A4 ABRASION RESISTANT ORGANOPOLYSILOXANE COATED POLYCARBONATE ARTICLE. GEN ELECTRIC (US) 1981-03-24 EP disclosed
EP-0020612-A1 ABRASION RESISTANT ORGANOPOLYSILOXANE COATED POLYCARBONATE ARTICLE GENERAL ELECTRIC COMPANY (US) 1981-01-07 EP disclosed
EP-0016870-A1 Process for polymerising methylmethacrylate, lamina produced from this polymer and its use RÖHM GMBH (DE) 1980-10-15 EP disclosed
WO-1980000940-A1 ABRASION RESISTANT ORGANOPOLYSILOXANE COATED POLYCARBONATE ARTICLE GEN ELECTRIC (US) 1980-05-15 WO disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed
US-4089839-A STABILIZERS/AGENTS UNIROYAL, INC. (US) 1978-05-16 US disclosed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12318459-B2 Thermoactive dental composite composition PUF60, POLQ, F10 KCNMA1 398/4885RAB9A 670/4885LMNA 871/4885
US-12186416-B2 Monomer mixture for producing a dental material PGM2, SCO2, B2M KCNMA1 251/4885RAB9A 4529/4885LMNA 276/4885
US-20250361349-A1 MONOMER MIXTURE FOR PRODUCING A DENTAL MATERIAL PGM2, ALG3, KCNMA1 KCNMA1 3/4885RAB9A 4449/4885LMNA 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.