Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886802 | 0.96 | NPC1 (0.70) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL483178 | 0.92 | PTPN1 (0.66) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL4188342 | 0.90 | NPC1 (0.52) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL6804880 | 0.89 | PTPN1 (0.79) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| N-Phenylbenzamide SCHEMBL8372230 | 0.87 | SIRT1 (0.80) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL10801344 | 0.87 | POLB (0.69) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24202631 | 0.85 | SIRT1 (0.83) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| SCHEMBL126415 | 0.85 | PTPN1 (0.87) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| N-Phenylbenzamide SCHEMBL31966 | 0.85 | SIRT1 (0.83) | PTPN1NPC1RAB9ASIRT1MEN1 | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.85 | SIRT1 (0.83) | PTPN1NPC1RAB9ASIRT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146922-A1 | C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID | DOMPE' FARMACEUTICI SPA (IT) | 2024-07-11 | — | — | WO | claimed |
| EP-4397306-A1 | C5AR1 INHIBITORS FOR USE IN THE TREATMENT OF OCULAR MUCOUS MEMBRANE PEMPHIGOID AND/OR ORAL MUCOUS MEMBRANE PEMPHIGOID | Dompe' Farmaceutici S.P.A. (IT) | 2024-07-10 | — | — | EP | claimed |
| CN-118184965-A | Polyimide-based polymer, and preparation method and application thereof | 华南师范大学 | 2024-06-14 | — | — | CN | claimed |
| US-20240180888-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | DOMPE' FARMACEUTICI SPA (IT) | 2024-06-06 | — | — | US | claimed |
| EP-4308114-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | Dompe' Farmaceutici SpA (IT) | 2024-01-24 | — | — | EP | claimed |
| CN-117337176-A | C5AR1 inhibitors for treating hypersensitivity to taxanes | 东佩制药股份公司 | 2024-01-02 | — | — | CN | claimed |
| US-11834532-B2 | Photoinitiators | IGH RESINS ITALIA S.R.L. (IT) | 2023-12-05 | — | — | US | claimed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | claimed |
| EP-3902878-A1 | PHOTOINITIATORS | IGM Resins Italia S.r.l. (IT) | 2021-11-03 | — | — | EP | claimed |
| CN-113518805-A | Photoinitiator | 意大利艾坚蒙树脂有限公司 | 2021-10-19 | — | — | CN | claimed |
| US-4178441-A | Enlarged-hetero-ring prostacylin analogs | THE UPJOHN COMPANY (US) | 1979-12-11 | — | — | US | claimed |
| US-4171447-A | Tri-halo prostaglandin intermediates | THE UPJOHN COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4158667-A | 6-Keto PGF analogs | THE UPJOHN COMPANY (US) | 1979-06-19 | — | — | US | claimed |
| US-4150222-A | (5E)-9-Deoxy-6,9-epoxy-prostaglandin derivatives | THE UPJOHN COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4125712-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-11-14 | — | — | US | claimed |
| US-4124601-A | Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds | THE UPJOHN COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| US-4080506-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-21 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-3979440-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | claimed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180888-A1 | C5AR1 INHIBITORS FOR TREATING HYPERSENSITIVITY REACTIONS TO TAXANES | C5AR1, C5AR2, C3AR1 | PTPN1 3009/4885NPC1 3083/4885RAB9A 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.