Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349118 | 0.90 | TSHR (0.55) | TSHR | |
| Acetic Acid SCHEMBL5485514 | 0.83 | FFAR3 (0.35) | TSHR | |
| SCHEMBL16237352 | 0.82 | TSHR (0.46) | TSHR | |
| Methacrylic Acid SCHEMBL28144780 | 0.75 | TSHR (0.39) | TSHR | |
| Acetic Acid SCHEMBL7262426 | 0.74 | FFAR3 (0.35) | TSHR | |
| Acetic Acid SCHEMBL1880325 | 0.74 | FFAR3 (0.35) | TSHR | |
| Acetic Acid SCHEMBL13719102 | 0.74 | FFAR3 (0.35) | TSHR | |
| SCHEMBL17628512 | 0.74 | TSHR (0.41) | TSHR | |
| Acetic Acid SCHEMBL7090485 | 0.74 | TDP1 (0.35) | TSHR | |
| 2-Methoxyethanol SCHEMBL28236376 | 0.73 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108850-A2 | COATING COMPOSITION AND METHOD OF APPLICATION | PERES CARL (US) | 2009-09-03 | — | — | WO | disclosed |
| US-20090220700-A1 | Coating Composition And Method Of Application | PERES CARL | 2009-09-03 | — | — | US | disclosed |