Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7262426 | 0.85 | FFAR3 (0.35) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL13719102 | 0.85 | FFAR3 (0.35) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL1880325 | 0.85 | FFAR3 (0.35) | FFAR3LCKFYNALDH1A1TSHR | |
| SCHEMBL430915 | 0.84 | MAPK1 (0.42) | MAPK1 | |
| Acetic Acid SCHEMBL4451384 | 0.83 | TSHR (0.44) | TSHR | |
| SCHEMBL9114511 | 0.81 | KMT2A (0.33) | ALDH1A1 | |
| Acetic Acid SCHEMBL27812087 | 0.81 | FFAR3 (0.32) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL2178814 | 0.81 | TSHR (0.48) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL25433223 | 0.79 | TSHR (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL7090485 | 0.79 | TDP1 (0.35) | FFAR3LCKFYNALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067706-A2 | PRESSURIZED AEROSOL FORMULATION FOR USE IN RADIATION SENSITIVE COATINGS | MICROCHEM CORP. (US) | 2007-06-14 | — | — | WO | claimed |
| US-20070134595-A1 | Pressurized aerosol formulation for use in radiation sensitive coatings | MICROCHEM CORP. | 2007-06-14 | — | — | US | claimed |
| WO-2007067706-A2 | PRESSURIZED AEROSOL FORMULATION FOR USE IN RADIATION SENSITIVE COATINGS | MICROCHEM CORP. (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20070134595-A1 | Pressurized aerosol formulation for use in radiation sensitive coatings | MICROCHEM CORP. | 2007-06-14 | — | — | US | disclosed |