SCHEMBL4451430

SCHEMBL4451430

O=P(Oc1cccc(-c2ccccc2)c1-c1ccccc1)(Oc1cccc(-c2ccccc2)c1-c1ccccc1)Oc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.40
HNF4A P41235 1/20 0.38
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
RAB9A P51151 2/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
ADRB2 P07550 1/20 0.35
HRH1 P35367 1/20 0.34
HTR7 P34969 1/20 0.34
RXRA P19793 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29604346 0.86 INPPL1 (0.52) GPR84HNF4AHDAC4HDAC2HDAC8
SCHEMBL4451434 0.86 INPPL1 (0.52) GPR84HNF4AHDAC4HDAC2HDAC8
SCHEMBL848183 0.84 BACE1 (0.40)
SCHEMBL3757937 0.84 NCOA1 (0.40) TDP1TP53NCOA1NCOA3MAPT
SCHEMBL473246 0.84 TDP1 (0.44) GPR84L3MBTL1TDP1RAB9ATP53
SCHEMBL28987121 0.83 GPR84 (0.46) GPR84HNF4AHDAC4HDAC2HDAC8
SCHEMBL3686702 0.83 INPPL1 (0.49) GPR84HNF4AHDAC4HDAC2HDAC8
SCHEMBL5374670 0.82 DPP4 (0.35) GPR84L3MBTL1TDP1RAB9ATP53
SCHEMBL1792077 0.80 BRD4 (0.35) GPR84L3MBTL1RAB9ATP53MAPT
SCHEMBL28679207 0.80 MAPT (0.36) GPR84L3MBTL1TDP1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113490705-A Thermosetting foam, method for producing same, and heat insulating material comprising same 乐金华奥斯有限公司 2021-10-08 CN disclosed
CN-108698389-B Multilayer film and method of manufacture 日本瑞翁株式会社 2020-04-28 CN disclosed
US-20090027586-A1 Thermoplastic Resin Composition, and Liquid Crystal Display Component Thereof or Information Recording Media Component Thereof POLYPLASTICS CO., LTD. (JP) 2009-01-29 US disclosed
EP-1992666-A1 THERMOPLASTIC RESIN COMPOSITION AND LIQUID CRYSTAL DISPLAY PART OR INFORMATION RECORDING MEDIUM PART USING THE COMPOSITION Polyplastics Co., Ltd. (JP) 2008-11-19 EP disclosed