SCHEMBL3757937

SCHEMBL3757937

Nc1ccc(-c2cccc(OP(=O)(Oc3cccc(-c4ccc(N)cc4)c3-c3ccc(N)cc3)Oc3cccc(-c4ccc(N)cc4)c3-c3ccc(N)cc3)c2-c2ccc(N)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 2/20 0.40
NCOA3 Q9Y6Q9 2/20 0.40
KDR P35968 3/20 0.37
KIT P10721 2/20 0.37
FLT3 P36888 2/20 0.37
CYP3A4 P08684 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TAAR1 Q96RJ0 2/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CHEK1 O14757 1/20 0.31
DAPK3 O43293 1/20 0.31
ABL1 P00519 1/20 0.31
PRKACA P17612 1/20 0.31
LTK P29376 1/20 0.31
LIMK1 P53667 1/20 0.31
ROCK1 Q13464 1/20 0.31
ALK Q9UM73 1/20 0.31
DYRK1B Q9Y463 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1160770 0.87 INPPL1 (0.47) NCOA1NCOA3KDRKITFLT3
SCHEMBL4451430 0.84 GPR84 (0.40) NCOA1NCOA3TDP1HSD17B10ALDH1A1
SCHEMBL848183 0.83 BACE1 (0.40) ABL1INPPL1INPP5BINPP5A
SCHEMBL3415275 0.81 MAP4K4 (0.41) MAPTFYN
SCHEMBL1792077 0.80 BRD4 (0.35) ALDH1A1TP53MAPT
SCHEMBL2446270 0.75 CYP3A4 (0.50) NCOA1NCOA3KDRKITFLT3
SCHEMBL38662435 0.73 ALDH1A1 (0.55) NCOA1NCOA3KDRKITFLT3
SCHEMBL3295751 0.73 HDAC4 (0.46)
SCHEMBL28679207 0.73 MAPT (0.36) TDP1ALDH1A1MAPT
SCHEMBL848184 0.72 INPPL1 (0.49) HSD17B10ALDH1A1ABL1INPPL1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2010-11-25 US disclosed
EP-2036911-A1 PROCESS FOR PRODUCTION OF AMINATED PHOSPHORIC ACID ESTER COMPOUND, FLAME-RETARDANT RESIN, AND FLAME-RETARDANT RESIN COMPOSITION SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-03-18 EP disclosed
EP-1513890-A1 HALOGEN FREE IGNITION RESISTANT THERMOPLASTIC RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-03-16 EP disclosed
WO-2003102060-A1 HALOGEN FREE IGNITION RESISTANT THERMOPLASTIC RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC. (US) 2003-12-11 WO disclosed
US-4499149-A ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES M&T CHEMICALS INC. (US) 1985-02-12 US disclosed
US-4480009-A POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE M&T CHEMICALS INC. (US) 1984-10-30 US disclosed
US-4395527-A POLYIMIDES FROM AMINOPOLYSILOXANES M & T CHEMICALS INC. (US) 1983-07-26 US disclosed
EP-0054426-A2 Improvements in or relating to siloxanes M & T CHEMICALS, INC. (US) 1982-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298506-A1 METHOD FOR PRODUCING AN AMINO GROUP-CONTAINING PHOSPHATE COMPOUND, AND A FLAME-RETARDANT RESIN AND FLAME-RETARDANT RESIN COMPOSITION ATIC, GART, RPP30 NCOA1 2214/4885NCOA3 1848/4885KDR 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.