SCHEMBL4451515

SCHEMBL4451515

CCCCCCCCCCCC(=O)Cc1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.50
CTBP2 P56545 1/20 0.49
CNR2 P34972 2/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
SHBG P04278 1/20 0.43
EPHX2 P34913 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4463081 1.00 P2RX7 (0.50) P2RX7CTBP2CNR2CES2CES1
SCHEMBL3642533 0.86 CTBP2 (0.54) CTBP2CNR2CES2CES1KMT2A
SCHEMBL28648015 0.85 CNR2 (0.48) P2RX7CNR2CES2CES1KMT2A
SCHEMBL11009522 0.81 L3MBTL1 (0.44) P2RX7KMT2AMAPT
SCHEMBL8679305 0.80 HTT (0.55) CTBP2CNR2CES2CES1BCHE
SCHEMBL2935824 0.80 CTBP2 (0.58) CTBP2KMT2AMEN1SHBGMAPT
SCHEMBL26444647 0.80 CYP3A4 (0.57) CNR2MAPT
SCHEMBL26444917 0.80 CYP3A4 (0.57) CNR2MAPT
SCHEMBL26444885 0.80 CYP3A4 (0.57) CNR2MAPT
SCHEMBL363774 0.78 CTBP2 (0.53) CTBP2KMT2AMEN1SHBGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US claimed
CN-100432129-C Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2008-11-12 CN claimed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP claimed
US-20060025503-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers PMC CINCINNATI, INC. 2006-02-02 US claimed
EP-1621576-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-02-01 EP claimed
CN-1727383-A Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2006-02-01 CN claimed
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
CN-100432129-C Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2008-11-12 CN disclosed
CN-101203556-A Stabiliser composition for chlorine-containing polymers SUN ACE KAKOH PTE LTD (SG) 2008-06-18 CN disclosed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP disclosed
US-20060025503-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers PMC CINCINNATI, INC. 2006-02-02 US disclosed
EP-1621576-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-02-01 EP disclosed
CN-1727383-A Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2006-02-01 CN disclosed
EP-0833861-A1 OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1998-04-08 EP disclosed
EP-0524354-B1 Polyvinylchloride composition and stabilizers therefor WITCO CORP (US) 1997-10-01 EP disclosed
US-5656202-A Method for making overbased PVC stabilizer WITCO CORPORATION (US) 1997-08-12 US disclosed
WO-1997000908-A1 OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1997-01-09 WO disclosed
WO-1997000907-A1 METHOD FOR MAKING OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1997-01-09 WO disclosed
EP-0524354-A1 Polyvinylchloride composition and stabilizers therefor WITCO CORPORATION (US) 1993-01-27 EP disclosed
US-5102933-A Heat resistance, discoloration inhibition WITCO CORPORATION (US) 1992-04-07 US disclosed