SCHEMBL4451524

SCHEMBL4451524

CC(C)(C)c1ccc(C(C)(OP(=O)(O)O)c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.[KH]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX5 P09917 1/20 0.33
PTGS2 P35354 1/20 0.33
NR1I2 O75469 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
RECQL P46063 1/20 0.33
HDAC1 Q13547 1/20 0.33
ACLY P53396 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4443601 0.97 ALDH1A1 (0.35) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4443731 0.97 ALDH1A1 (0.35) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4447592 0.87 ALDH1A1 (0.35) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL10447765 0.86 ACLY (0.33) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4960067 0.86 ALDH1A1 (0.33) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL9330560 0.86 ALDH1A1 (0.34) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4446418 0.85 ALDH1A1 (0.32) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4447601 0.85 ALDH1A1 (0.32) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL4447781 0.83 ALDH1A1 (0.30) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL1788391 0.78 ALDH1A1 (0.42) ALDH1A1TDP1ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1108733-B1 Propylene-ethylene block copolymer, resin composition, and blow-molded article PRIME POLYMER CO LTD (JP) 2008-05-07 EP disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-20040106738-A1 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-06-03 US disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed
EP-1108733-A1 Propylene-ethylene block copolymer, resin composition, and blow-molded article IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-06-20 EP disclosed