Threonine

Threonine

SCHEMBL4451758

C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)OC(=O)[C@H](C)N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.46
SLC1A3 P43003 7/20 0.40
SLC1A2 P43004 7/20 0.40
SLC1A1 P43005 7/20 0.40
TP53 P04637 1/20 0.36
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
ACHE P22303 1/20 0.32
LAP3 P28838 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL8429461 0.89 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL3191865 0.86 SLC7A5 (0.33) SLC7A5
Threonine SCHEMBL5073183 0.85 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL1811514 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL3209332 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL17113858 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL1811511 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL16982373 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL1514133 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Threonine SCHEMBL4205142 0.84 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2SLC1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101341615-B Fuel cell and electrolyte layer for fuel cell TOYOTA MOTOR CO LTD 2010-05-19 CN disclosed
US-20090136814-A1 FUEL CELL AND ELECTROLYTE LAYER FOR FUEL CELL TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2009-05-28 US disclosed
CN-101341615-A Fuel cell and electrolyte layer for fuel cell TOYOTA MOTOR CO LTD (JP) 2009-01-07 CN disclosed
EP-0948652-A4 INSECT SODIUM CHANNELS FROM INSECTICIDE-SUSCEPTIBLE AND INSECTICIDE-RESISTANT HOUSE FLIES CORNELL RES FOUNDATION INC (US) 2002-01-02 EP disclosed
EP-0948652-A1 INSECT SODIUM CHANNELS FROM INSECTICIDE-SUSCEPTIBLE AND INSECTICIDE-RESISTANT HOUSE FLIES CORNELL RESEARCH FOUNDATION, INC. (US) 1999-10-13 EP disclosed
WO-1998028446-A1 INSECT SODIUM CHANNELS FROM INSECTICIDE-SUSCEPTIBLE AND INSECTICIDE-RESISTANT HOUSE FLIES CORNELL RESEARCH FOUNDATION, INC. (US) 1998-07-02 WO disclosed