Threonine

Threonine

SCHEMBL5073183

C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)OC(=O)CN

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.38
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
GABRR1 P24046 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL6856748 0.98 SLC7A5 (0.36) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL2765872 0.91 SLC7A5 (0.39) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL8429461 0.86 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL4451758 0.85 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL1537296 0.85 GRIN2D (0.33) SLC7A5GABRR1
SCHEMBL186138 0.85 GRIN2D (0.33) SLC7A5GABRR1
SCHEMBL442281 0.83 SLC7A5 (0.30) SLC7A5
SCHEMBL1675353 0.81 SLC7A5 (0.33) SLC7A5SLC1A3SLC1A2SLC1A1
Serine SCHEMBL5698241 0.80 SLC7A5 (0.33) SLC7A5SLC1A3SLC1A2SLC1A1USP2
Threonine SCHEMBL6367180 0.79 METAP2 (0.35) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979046-A2 GALVANIC CURRENT SKIN TREATMENT Nu Skin International, Inc. (US) 2008-10-15 EP disclosed
WO-2007092796-A2 GALVANIC CURRENT SKIN TREATMENT NU SKIN INTERNATIONAL, INC. (US) 2007-08-16 WO disclosed