Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308807 | 0.92 | ALDH1A1 (0.54) | TSHRSMN1; SMN2MMP2PTGS2CA1 | |
| Chlorobenzene SCHEMBL9364353 | 0.92 | TSHR (0.68) | TSHRSMN1; SMN2MMP2PTGS2CA1 | |
| SCHEMBL1759743 | 0.90 | TSHR (0.73) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| Benzene SCHEMBL28284524 | 0.89 | TSHR (0.64) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| SCHEMBL30029777 | 0.89 | TSHR (0.71) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| SCHEMBL21993467 | 0.89 | TSHR (0.71) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| SCHEMBL15849846 | 0.89 | TSHR (0.71) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| SCHEMBL34718 | 0.89 | TSHR (0.71) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| SCHEMBL11746268 | 0.87 | TSHR (0.68) | TSHRSMN1; SMN2MMP2CA1CA2 | |
| Hydrochloric Acid SCHEMBL8381085 | 0.87 | TSHR (0.68) | TSHRSMN1; SMN2MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144244-A1 | Stable compositions of S-adenosyl-l-methionine with dextran | HEBERT SAM-E LLC | 2003-07-31 | — | — | US | claimed |
| US-20090012036-A1 | Stable S-adenosyl-L-methionine | HEBERT SAM-E LLC | 2009-01-08 | — | — | US | disclosed |
| US-20050272687-A1 | Stable S-adenosyl-l-methionine | HEBERT ROLLAND F | 2005-12-08 | — | — | US | disclosed |
| US-20040063660-A1 | Diasteriomers of S-adenosyl-l-methionine and uses thereof | HEBERT ROLLAND F (US) | 2004-04-01 | — | — | US | disclosed |