Chlorobenzene

Chlorobenzene

SCHEMBL9364353

Clc1ccccc1.O=S(=O)(O)c1ccc(Cl)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
POLB P06746 1/20 0.57
CYP2D6 P10635 1/20 0.57
ALDH1A1 P00352 2/20 0.54
CYP3A4 P08684 1/20 0.54
MAPK1 P28482 1/20 0.54
LMNA P02545 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
FLT1 P17948 1/20 0.52
FLT4 P35916 1/20 0.52
KDR P35968 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759743 0.98 TSHR (0.73) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
Benzene SCHEMBL28284524 0.98 TSHR (0.64) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
Chlorobenzene SCHEMBL29026484 0.93 TSHR (0.80) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL8746207 0.93 ALDH1A1 (0.62) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL26836 0.93 ALDH1A1 (0.62) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL8477054 0.93 ALDH1A1 (0.62) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL4452026 0.92 CYP1A2 (0.60) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL8714706 0.90 ALDH1A1 (0.59) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
SCHEMBL6568407 0.90 ALDH1A1 (0.59) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1
Ammonia Solution, Strong SCHEMBL11740925 0.90 ALDH1A1 (0.59) TSHRSMN1; SMN2POLBCYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6116231-A None JP disclosed
JP-H06116231-A PURIFICATION OF 4,4'-DICHLORODIPHENYLSULFONE UBE IND LTD 1994-04-26 JP disclosed