Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.53 |
| ▸ | CCR4 | P51679 | 5/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113927 | 0.85 | CYP2D6 (0.60) | CCR4 | |
| SCHEMBL8183557 | 0.85 | CACNA2D1 (0.64) | CACNA2D1CCR4 | |
| SCHEMBL5189439 | 0.81 | LMNA (0.64) | CCR4 | |
| SCHEMBL711137 | 0.75 | CHRM2 (0.76) | CACNA2D1HSP90AA1HSP90AB1 | |
| SCHEMBL31366023 | 0.74 | MEN1 (0.42) | — | |
| SCHEMBL709359 | 0.70 | CHRM2 (0.80) | CACNA2D1HSP90AA1HSP90AB1 | |
| SCHEMBL5471335 | 0.69 | CACNA2D1 (1.00) | CACNA2D1CCR4 | |
| SCHEMBL3878308 | 0.69 | CACNA2D1 (1.00) | CACNA2D1CCR4 | |
| SCHEMBL31500268 | 0.68 | USP2 (0.76) | CACNA2D1 | |
| SCHEMBL31366043 | 0.68 | CYP3A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261340-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE | ALPHA RES GROUP LLC (US) | 2009-05-13 | — | — | EP | disclosed |