Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754130 | 0.84 | MAPK1 (0.70) | ALDH1A1PKML3MBTL1MAPK1KMT2A | |
| SCHEMBL19371259 | 0.82 | KMT2A (0.64) | ALDH1A1PKML3MBTL1MAPK1KMT2A | |
| SCHEMBL3774595 | 0.81 | MAPK1 (0.69) | ALDH1A1PKML3MBTL1MAPK1KMT2A | |
| SCHEMBL3430128 | 0.81 | S1PR3 (0.40) | ALDH1A1PKML3MBTL1MAPK1GAA | |
| SCHEMBL16540985 | 0.78 | PLAU (0.36) | ALDH1A1PKML3MBTL1MAPK1GAA | |
| SCHEMBL14921128 | 0.77 | L3MBTL1 (0.60) | ALDH1A1PKML3MBTL1MAPK1KMT2A | |
| SCHEMBL783927 | 0.76 | MAPK1 (0.56) | ALDH1A1PKML3MBTL1MAPK1KMT2A | |
| SCHEMBL28409115 | 0.76 | MAPK1 (0.56) | ALDH1A1PKMMAPK1KMT2AGAA | |
| SCHEMBL2888813 | 0.76 | MAPK1 (0.87) | ALDH1A1L3MBTL1MAPK1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL784570 | 0.75 | L3MBTL1 (0.59) | ALDH1A1PKML3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694648-B1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER SAS (FR) | 2015-07-29 | — | — | EP | disclosed |
| EP-1694649-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-01-22 | — | — | EP | disclosed |
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| US-7572818-B2 | Fungicides; N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-iodobenzamide; -{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-bromobenzamide | BAYER CROPSCIENCE S.A. (FR) | 2009-08-11 | — | — | US | disclosed |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2007-05-24 | — | — | US | disclosed |
| EP-1694648-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | Bayer CropScience S.A. (FR) | 2006-08-30 | — | — | EP | disclosed |
| EP-1694649-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2006-08-30 | — | — | EP | disclosed |
| EP-1531673-B1 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2006-01-04 | — | — | EP | disclosed |
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | BAYER SAS (FR) | 2005-10-20 | — | — | US | disclosed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058833-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | disclosed |
| EP-1548007-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| EP-1531673-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004016088-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389614-A1 | Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides | Bayer CropScience S.A. (FR) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | PNPO, PAH, CNPY2 | ALDH1A1 2346/4885PKM 1147/4885L3MBTL1 1861/4885 |
| US-20070117845-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | CYP1A2, PNPO, PFAS | ALDH1A1 1103/4885PKM 503/4885L3MBTL1 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.