Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436302 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL11570605 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL9137944 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EGSTP1 | |
| SCHEMBL12507833 | 0.76 | ALDH1A1 (0.97) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7708092 | 0.75 | SLC6A2 (0.45) | ALDH1A1MEN1KMT2AGSTP1MAPT | |
| SCHEMBL7708087 | 0.75 | SLC6A2 (0.45) | ALDH1A1MEN1KMT2AGSTP1MAPT | |
| (Z)-1,2-Diphenylethene SCHEMBL28808571 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL10784403 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EOPRM1GSTP1MAPT | |
| SCHEMBL17844735 | 0.74 | OPRM1 (0.52) | ALDH1A1MEN1KMT2AMGLLKDM4E | |
| SCHEMBL17844772 | 0.74 | OPRM1 (0.52) | ALDH1A1MEN1KMT2AMGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521781-B1 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORP (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-7405262-B2 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20060036050-A1 | Preparation of functionalized anionic polymerization initiators | BRIDGESTONE CORPORATION (JP) | 2006-02-16 | — | — | US | disclosed |
| EP-1521781-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | Bridgestone Corporation (JP) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007563-A2 | PREPARATION OF FUNCTIONALIZED ANIONIC POLYMERIZATION INITIATORS | BRIDGESTONE CORPORATION (JP) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036050-A1 | Preparation of functionalized anionic polymerization initiators | PKD1, ALG8, ALG3 | ALDH1A1 3921/4885MEN1 1043/4885KMT2A 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.