SCHEMBL4452321

SCHEMBL4452321

Cl[Si](Cl)(Cl)C1=CC2CCC1C2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5385537 0.83
SCHEMBL483868 0.77 CYP19A1 (0.31) CYP19A1
SCHEMBL6841964 0.74 CYP19A1 (0.33) CYP19A1
SCHEMBL6696216 0.74 CYP19A1 (0.33) CYP19A1
SCHEMBL2122664 0.72 CYP19A1 (0.32) CYP19A1
SCHEMBL8851736 0.72 CYP19A1 (0.35) CYP19A1
SCHEMBL6537566 0.72 CYP19A1 (0.32) CYP19A1
SCHEMBL9320032 0.72 CYP19A1 (0.32) CYP19A1
SCHEMBL4944053 0.71 CYP19A1 (0.31) CYP19A1
SCHEMBL236510 0.69 CYP19A1 (0.33) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507579-B2 Apparatus and methods for simultaneous operation of miniaturized reactors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-03-24 US disclosed
WO-2007038572-A2 MICROBIOREACTOR FOR CONTINUOUS CELL CULTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-04-05 WO disclosed
US-7108914-B2 Self-healing polymer compositions MOTOROLA, INC. (US) 2006-09-19 US disclosed
US-20060199260-A1 Microbioreactor for continuous cell culture MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2006-09-07 US disclosed
WO-2006037022-A2 MICROBIOREACTOR FOR CONTINUOUS CELL CULTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-04-06 WO disclosed
WO-2005097969-A1 APPARATUS AND METHODS FOR SIMULTANEOUS OPERATION OF MINIATURIZED REACTORS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-10-20 WO disclosed
US-20050089993-A1 Apparatus and methods for simultaneous operation of miniaturized reactors MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2005-04-28 US disclosed
EP-1499705-A2 MICROFERMENTORS FOR RAPID SCREENING AND ANALYSIS OF BIOCHEMICAL PROCESSES Massachusetts Institute of Technology (US) 2005-01-26 EP disclosed
US-6844263-B2 LSI device polishing composition and method for producing LSI device SHOWA DENKO KABUSHIKI KAISHA (JP) 2005-01-18 US disclosed
US-20040242782-A1 Rubber composition and vulcanized rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-12-02 US disclosed
US-20030153188-A1 LSI device polishing composition and method for producing LSI device SHOWA DENKO K.K. 2003-08-14 US disclosed
US-6547843-B2 For polishing metal layer formed of copper and a thin film formed of tantalum or tantalum nitride for large scale integration device SHOWA DENKO K.K. (JP) 2003-04-15 US disclosed
US-20020017064-A1 LSI device polishing composition and method for reproducing LSI device SHOWA DENKO K.K. (JP) 2002-02-14 US disclosed
US-6031058-A POLYMERS OF THE INVENTION INCLUDE POLYCYCLIC REPEAT UNITS THAT CONTAIN PENDANT SILYL FUNCTIONAL GROUPS THE B.F. GOODRICH COMPANY (US) 2000-02-29 US disclosed
US-5912313-A MOLDINGS, COATINGS, ADHESIVES, MEMBRANES; OXIDATION, HEAT AND CHEMICAL RESISTANCE; DIELECTRICS, INTEGRATED CIRCUITS THE B. F. GOODRICH COMPANY (US) 1999-06-15 US disclosed
EP-0095787-A1 Coupling process for living polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-12-07 EP disclosed
US-4408017-A STAR POLYMERS SHELL OIL COMPANY (US) 1983-10-04 US disclosed
US-4216024-A Process for producing mineral fillers with graft peroxy groups for polymers ENIKOLOPOV NIKOLAI S (SU) 1980-08-05 US disclosed
US-4214914-A Method for producing mineral fillers containing graft hydroperoxide groups for use with polymers ENIKOLOPOV NIKOLAI S (SU) 1980-07-29 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed