SCHEMBL5385537

SCHEMBL5385537

C[Si](Cl)(Cl)C1=CC2CCC1C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452321 0.83 CYP19A1 (0.31)
SCHEMBL483868 0.83 CYP19A1 (0.31)
SCHEMBL6696216 0.79 CYP19A1 (0.33)
SCHEMBL6841964 0.79 CYP19A1 (0.33)
SCHEMBL2122664 0.78 CYP19A1 (0.32)
SCHEMBL9320032 0.78 CYP19A1 (0.32)
SCHEMBL4944053 0.76 CYP19A1 (0.31)
SCHEMBL445871 0.73 CYP19A1 (0.32)
SCHEMBL8851736 0.73 CYP19A1 (0.35)
SCHEMBL6537566 0.73 CYP19A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189868-B2 Cyclic siloxane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-03-13 US disclosed
US-20060264649-A1 Novel cyclic siloxane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-11-23 US disclosed
US-20040242782-A1 Rubber composition and vulcanized rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-12-02 US disclosed
EP-0095787-A1 Coupling process for living polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-12-07 EP disclosed
US-4408017-A STAR POLYMERS SHELL OIL COMPANY (US) 1983-10-04 US disclosed