Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | MYLK | Q15746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4446566 | 0.99 | NSD2 (0.71) | NSD2MCL1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL4446610 | 0.91 | NSD2 (0.73) | NSD2MCL1TP53 | |
| Hydrochloric Acid SCHEMBL4445435 | 0.90 | NSD2 (0.74) | NSD2MCL1TP53 | |
| SCHEMBL4454417 | 0.88 | NSD2 (0.78) | NSD2MCL1 | |
| Hydrochloric Acid SCHEMBL4444954 | 0.86 | NSD2 (0.78) | NSD2MCL1 | |
| SCHEMBL4444964 | 0.84 | NSD2 (0.68) | NSD2CYP3A4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4448428 | 0.84 | NSD2 (0.80) | NSD2 | |
| Hydrochloric Acid SCHEMBL4455040 | 0.83 | NSD2 (0.69) | NSD2CYP3A4KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4441197 | 0.83 | NSD2 (1.00) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444943 | 0.83 | NSD2 (0.81) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |