Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444949 | 0.92 | NSD2 (0.84) | NSD2NPY5R | |
| Hydrochloric Acid SCHEMBL4445112 | 0.90 | NSD2 (0.85) | NSD2NPY5R | |
| SCHEMBL4450802 | 0.90 | NSD2 (0.82) | NSD2NPY5R | |
| Hydrochloric Acid SCHEMBL4445018 | 0.88 | NSD2 (0.82) | NSD2NPY5R | |
| SCHEMBL4445013 | 0.88 | NSD2 (1.00) | NSD2 | |
| SCHEMBL4446973 | 0.88 | NSD2 (0.77) | NSD2NPY5R | |
| SCHEMBL4454417 | 0.87 | NSD2 (0.78) | NSD2 | |
| SCHEMBL4443335 | 0.87 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4445433 | 0.87 | NSD2 (1.00) | NSD2 | |
| SCHEMBL4443035 | 0.87 | NSD2 (0.77) | NSD2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20040234622-A1 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040234622-A1 | Sulfonamide derivatives | PCNA, TOP2A, DDB1 | NSD2 122/4885NPY5R 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.