SCHEMBL4454417

SCHEMBL4454417

Nc1cccc2c(S(=O)(=O)NCc3ccc(Cl)cc3)cccc12

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 16/20 0.78
MCL1 Q07820 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CNR1 P21554 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4444954 0.99 NSD2 (0.78) NSD2MCL1MEN1KMT2ACNR1
SCHEMBL4450802 0.89 NSD2 (0.82) NSD2
SCHEMBL4452473 0.88 NSD2 (0.71) NSD2MCL1
SCHEMBL4445013 0.87 NSD2 (1.00) NSD2
Hydrochloric Acid SCHEMBL4445018 0.87 NSD2 (0.82) NSD2
SCHEMBL4441197 0.87 NSD2 (1.00) NSD2
Hydrochloric Acid SCHEMBL4446566 0.86 NSD2 (0.71) NSD2MCL1
SCHEMBL4446610 0.86 NSD2 (0.73) NSD2MCL1CNR1
SCHEMBL4443335 0.86 NSD2 (0.78) NSD2CNR1
Hydrochloric Acid SCHEMBL4445433 0.86 NSD2 (1.00) NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7547716-B2 Sulfonamide derivatives INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2009-06-16 US claimed