SCHEMBL4452600

SCHEMBL4452600

FCC(Cl)(Cl)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19460651 0.76
SCHEMBL10752274 0.73
SCHEMBL7451605 0.71
SCHEMBL16823915 0.69
SCHEMBL869267 0.67
SCHEMBL9684312 0.65
SCHEMBL1992906 0.64
SCHEMBL1148286 0.64
SCHEMBL9851075 0.64
Norflurane SCHEMBL9125116 0.64 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590052-B2 Azeotropic compositions of hydrogen fluoride and Z-3,3,3-trifluoro-1-chloropropene ARKEMA FRANCE (FR) 2020-03-17 US disclosed
US-20180297919-A1 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE ARKEMA FRANCE (FR) 2018-10-18 US disclosed
US-10029961-B2 Azeotropic compositions of hydrogen fluoride and Z-3,3,3-trifluoro-1-chloropropene ARKEMA FRANCE (FR) 2018-07-24 US disclosed
EP-3083537-B1 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE ARKEMA FRANCE (FR) 2018-05-23 EP disclosed
US-20170297982-A1 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE ARKEMA FRANCE (FR) 2017-10-19 US disclosed
EP-3083537-A1 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE Arkema France (FR) 2016-10-26 EP disclosed
CN-105829270-A Azeotropic Compositions Of Hydrogen Fluoride And Z-3,3,3-Trifluoro-1-Chloropropene 阿科玛法国公司 2016-08-03 CN disclosed
WO-2015092211-A1 AZEOTROPIC COMPOSITIONS OF HYDROGEN FLUORIDE AND Z-3,3,3-TRIFLUORO-1-CHLOROPROPENE ARKEMA FRANCE (FR) 2015-06-25 WO disclosed
EP-2121548-A2 PROCESS FOR THE PREPARATION OF C3-7 FLUOROALKENES BY BASE-MEDIATED DEHYDROHALOGENATATION OF HYDROHALOGENATED C3-7 FLUOROALKANES Ineos Fluor Holdings Limited (GB) 2009-11-25 EP disclosed
WO-2008075017-A2 PROCESS FOR THE PREPARATION OF C3-7 FLUOROALKENES BY BASE-MEDIATED DEHYDROHALOGENATATION OF HYDROHALOGENATED C3 -7 FLUOROALKANES INEOS FLUOR HOLDINGS LIMITED (GB) 2008-06-26 WO disclosed