Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 2/20 | 0.74 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452808 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL5851373 | 0.93 | GLO1 (0.88) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL5851384 | 0.93 | GLO1 (0.88) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL4454234 | 0.88 | GLO1 (0.81) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL4454233 | 0.88 | GLO1 (0.81) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL4465315 | 0.87 | GLO1 (1.00) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL4465316 | 0.87 | GLO1 (1.00) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL6417375 | 0.84 | GLO1 (0.79) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL27870367 | 0.83 | MEN1 (0.76) | MEN1KMT2AMAPTTDP1HTT | |
| SCHEMBL15825851 | 0.82 | GLO1 (1.00) | MEN1KMT2AMAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |