SCHEMBL6417375

SCHEMBL6417375

CC(=O)c1ccc(N=Nc2ccc(O)c3ncccc23)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 6/20 0.79
RPS6KA3 P51812 1/20 0.79
MEN1 O00255 9/20 0.72
KMT2A Q03164 9/20 0.72
MAPT P10636 8/20 0.72
TDP1 Q9NUW8 6/20 0.72
HTT P42858 5/20 0.72
L3MBTL1 Q9Y468 5/20 0.72
SMN1; SMN2 Q16637 5/20 0.72
LMNA P02545 3/20 0.72
KCNH2 Q12809 2/20 0.72
ALDH1A1 P00352 2/20 0.72
MAPK1 P28482 5/20 0.67
RAB9A P51151 4/20 0.67
HSP90AA1 P07900 4/20 0.67
KDM4E B2RXH2 4/20 0.67
ATM Q13315 2/20 0.67
OPRK1 P41145 2/20 0.67
NPC1 O15118 4/20 0.66
CASP6 P55212 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13187381 0.88 GLO1 (1.00) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL15825851 0.88 GLO1 (1.00) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL5851373 0.88 GLO1 (0.88) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL5851384 0.88 GLO1 (0.88) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL27899124 0.87 GLO1 (0.97) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL4452808 0.84 MEN1 (1.00) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL4452805 0.84 MEN1 (1.00) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL4454234 0.84 GLO1 (0.81) GLO1RPS6KA3MEN1KMT2AMAPT
SCHEMBL4454233 0.84 GLO1 (0.81) GLO1RPS6KA3MEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL4461693 0.83 MEN1 (0.66) GLO1RPS6KA3MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521846-B1 SERRS REACTIVE PARTICLES UNIV STRATHCLYDE (GB) 2013-03-06 EP disclosed
US-20050130163-A1 Serrs reactive particles STRATHCLYDE, UNIVERSITY OF (GB) 2005-06-16 US disclosed