Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496196 | 0.93 | SLC6A9 (0.35) | SLC6A9CNR1USP2TYRO3MERTK | |
| SCHEMBL3684175 | 0.93 | SLC6A9 (0.35) | SLC6A9CNR1USP2TYRO3MERTK | |
| SCHEMBL3690048 | 0.88 | SLC6A9 (0.34) | SLC6A9USP2TYRO3MERTK | |
| SCHEMBL7501105 | 0.88 | SLC6A9 (0.34) | SLC6A9USP2TYRO3MERTK | |
| SCHEMBL7500064 | 0.86 | USP2 (0.33) | USP2 | |
| SCHEMBL7491631 | 0.86 | TACR1 (0.34) | USP2 | |
| SCHEMBL3650212 | 0.86 | TACR1 (0.34) | USP2 | |
| SCHEMBL3690401 | 0.86 | USP2 (0.33) | USP2 | |
| SCHEMBL3692133 | 0.85 | PDE4B (0.34) | SLC6A9 | |
| SCHEMBL7495706 | 0.85 | PDE4B (0.34) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | GLAXOSMITHKLINE LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | OAT, HAVCR2, CPS1 | SLC6A9 4294/4885CNR1 524/4885SFRP1 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.