Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452899 | 1.00 | NPC1 (0.45) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL4455581 | 0.87 | CTSS (0.43) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL4455577 | 0.87 | CTSS (0.43) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL13408965 | 0.86 | NPC1 (0.48) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL21583693 | 0.85 | NPC1 (0.47) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL4470020 | 0.85 | S1PR3 (0.51) | RAB9ACTSSMAPT | |
| SCHEMBL4468902 | 0.83 | NPC1 (0.39) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL7682517 | 0.82 | NPC1 (0.51) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL7682513 | 0.82 | NPC1 (0.51) | NPC1RAB9AGAACSNK1DSCD | |
| SCHEMBL4456266 | 0.82 | CTSS (0.45) | NPC1RAB9AGAACSNK1DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |