Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 16/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452895 | 0.85 | NPC1 (0.45) | MAPTRAB9ACTSS | |
| SCHEMBL4452899 | 0.85 | NPC1 (0.45) | MAPTRAB9ACTSS | |
| SCHEMBL13408924 | 0.83 | S1PR3 (0.55) | S1PR3S1PR4MAPTRAB9ACTSL | |
| SCHEMBL2418767 | 0.82 | S1PR3 (0.48) | S1PR3S1PR4MAPTRAB9ACTSL | |
| SCHEMBL2418764 | 0.82 | S1PR3 (0.48) | S1PR3S1PR4MAPTRAB9ACTSL | |
| SCHEMBL4457075 | 0.74 | FBP1 (0.40) | MAPTFBP1 | |
| SCHEMBL4455577 | 0.73 | CTSS (0.43) | MAPTRAB9ACTSS | |
| SCHEMBL4455581 | 0.73 | CTSS (0.43) | MAPTRAB9ACTSS | |
| SCHEMBL13408965 | 0.71 | NPC1 (0.48) | MAPTRAB9ACTSS | |
| SCHEMBL21583693 | 0.70 | NPC1 (0.47) | MAPTRAB9ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |