SCHEMBL4452908

SCHEMBL4452908

Clc1cccc(Cl)c1-c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP2A6 P11509 2/20 0.45
TSHR P16473 4/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PNMT P11086 2/20 0.40
CES1 P23141 1/20 0.38
PDK2 Q15119 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
RET P07949 1/20 0.35
GRK5 P34947 1/20 0.35
TYRO3 Q06418 1/20 0.35
DYRK1B Q9Y463 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471569 0.87 TSHR (0.57) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL4453792 0.82 TSHR (0.46) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL4447158 0.79 TSHR (0.48) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL29816658 0.79 TSHR (0.48) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL4448496 0.78 CYP3A4 (0.48) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL7766914 0.78 PDK2 (0.40) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL5948479 0.78 TSHR (0.54) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL4452879 0.75 TSHR (0.50) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL29367755 0.75 CYP3A4 (0.39) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL4454468 0.75 CYP3A4 (0.39) CYP1A2CYP2A6TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-114270671-A Cover assembly with vehicle-mounted generator for railway vehicle and axle assembly comprising cover assembly 环球商业有限公司 2022-04-01 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed