SCHEMBL4452879

SCHEMBL4452879

Clc1cc(Cl)c(-c2c(Cl)cccc2Cl)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.50
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 3/20 0.50
HSD17B10 Q99714 3/20 0.50
RECQL P46063 2/20 0.50
HSP90AA1 P07900 1/20 0.48
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
LMNA P02545 2/20 0.44
AHR P35869 3/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471569 0.87 TSHR (0.57) TSHRALDH1A1HSP90AA1CYP1A2CYP2A6
SCHEMBL2937097 0.83 TSHR (0.67) TSHRALDH1A1CYP3A4HSD17B10RECQL
SCHEMBL4448496 0.78 CYP3A4 (0.48) TSHRALDH1A1CYP3A4HSD17B10HSP90AA1
SCHEMBL4448776 0.77 AHR (0.46) TSHRALDH1A1HSP90AA1CYP1A2CYP2A6
SCHEMBL4459139 0.77 ALDH1A1 (0.50) TSHRALDH1A1CYP3A4HSD17B10RECQL
SCHEMBL29389611 0.77 ALDH1A1 (0.50) TSHRALDH1A1CYP3A4HSD17B10RECQL
SCHEMBL4453792 0.77 TSHR (0.46) TSHRALDH1A1CYP3A4HSD17B10RECQL
SCHEMBL4456396 0.76 ALDH1A1 (0.50) TSHRALDH1A1HSD17B10HSP90AA1CYP1A2
SCHEMBL4456481 0.76 ALDH1A1 (0.43) TSHRALDH1A1HSP90AA1AHRMAPK1
SCHEMBL4453603 0.76 AHR (0.50) TSHRALDH1A1CYP3A4HSD17B10HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-120114486-A Application of Escherichia coli-derived minicells in degradation of phenylalanine 中国农业大学 2025-06-10 CN disclosed
CN-113314494-B Semiconductor device with flexible connector array 美光科技公司 2025-05-09 CN disclosed
CN-119934912-A High-precision automatic test fuze detector structure and installation test method 武汉星伴通信设备有限责任公司 2025-05-06 CN disclosed
CN-119153975-A Spring member for antenna contacts 普卢姆设计有限公司 2024-12-17 CN disclosed
CN-114727573-B Sensor device and ground connection 梅斯法国公司 2024-11-22 CN disclosed
CN-118920853-A General three-dimensional integrated converter structure 西安交通大学 2024-11-08 CN disclosed
WO-2024142147-A1 FLAVOR GENERATION ARTICLE, FLAVOR INHALATION SYSTEM, AND METHOD FOR PRODUCING FLAVOR GENERATION ARTICLE 日本たばこ産業株式会社 2024-07-04 WO disclosed
WO-2024142148-A1 FLAVOR INHALATION SYSTEM 日本たばこ産業株式会社 2024-07-04 WO disclosed
WO-2024127576-A1 FLAVOR-GENERATING ARTICLE AND FLAVOR INHALATION SYSTEM 日本たばこ産業株式会社 2024-06-20 WO disclosed
CN-111141930-B MEMS accelerometer anti-reflection and reflector coatings 通用电气公司 2022-07-05 CN disclosed
CN-114583432-A Semiconductor device with substrate integrated hollow waveguide and method thereof 恩智浦有限公司 2022-06-03 CN disclosed
CN-216357317-U Earphone shell packaging equipment 东莞市猎声电子科技有限公司 2022-04-19 CN disclosed
CN-114207939-A Antenna design for robust cross-head and cross-body linking 谷歌有限责任公司 2022-03-18 CN disclosed
CN-114207395-A Passive infrared sensor system and method 得克萨斯农工大学系统 2022-03-18 CN disclosed
CN-114144008-A Integrated display module 南京信为峰光电科技有限公司 2022-03-04 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed