SCHEMBL4452962

SCHEMBL4452962

Clc1ccc(-c2c(Cl)cc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.56
TP53 P04637 1/20 0.52
HSD11B1 P28845 2/20 0.48
TSHR P16473 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
S100A4 P26447 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HSP90AA1 P07900 2/20 0.44
HSP90AB1 P08238 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
RAB9A P51151 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SRD5A2 P31213 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453603 0.87 AHR (0.50) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL29624840 0.85 AHR (0.64) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL464507 0.85 AHR (0.64) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL4445166 0.84 AHR (0.58) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL4456273 0.84 AHR (0.57) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL4459802 0.82 AHR (0.61) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL29489601 0.81 TP53 (0.57) AHRTP53TSHRCYP3A4HSD17B10
SCHEMBL2852592 0.81 TP53 (0.57) AHRTP53TSHRCYP3A4HSD17B10
SCHEMBL4450039 0.80 AHR (0.54) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL29624837 0.80 AHR (0.54) AHRTP53HSD11B1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116632237-A Positive and negative electrode material of alkaline battery and preparation method thereof 余姚市中盛电子科技有限公司 2023-08-22 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-122074003-A Package structure and method for forming the same 台湾积体电路制造股份有限公司 2026-05-22 CN disclosed
CN-224223229-U Main control PCB sub-assembly tool of automatic gear shifter of automobile 柳州市金元机械制造有限公司 2026-05-12 CN disclosed
US-20250335568-A1 EMI ANOMALY DETECTION IN COMPUTER SYSTEMS USING ANTENNA IN EXPANSION CARD FORM FACTOR ORACLE INT CORP (US) 2025-10-30 US disclosed
WO-2025123345-A1 MEMORY ARRAY, MANUFACTURING METHOD THEREFOR, MEMORY AND ELECTRONIC DEVICE 华为技术有限公司 2025-06-19 WO disclosed
CN-222827433-U Multilayer PCB (printed circuit board) superposition connection structure 信利光电股份有限公司 2025-05-02 CN disclosed
CN-119653601-A PCB routing processing method 广州市合成电子制品有限公司 2025-03-18 CN disclosed
CN-109473854-B HDMI line automatic plug device 深圳市明信测试设备股份有限公司 2025-02-28 CN disclosed
CN-119447125-A Chip stacking structure, electronic equipment and preparation method of chip stacking structure 华为技术有限公司 2025-02-14 CN disclosed
WO-2025031223-A1 BATTERY MODULE 惠州亿纬锂能股份有限公司 2025-02-13 WO disclosed
CN-114068432-A Novel SOT-236 深圳天德钰科技股份有限公司 2022-02-18 CN disclosed
CN-113993274-A SIP module and mobile terminal 惠州TCL移动通信有限公司 2022-01-28 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
US-20010031759-A1 Novel heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases DR. REDDY'S RESEARCH FOUNDATION & REDDY- CHEMINOR, INC. 2001-10-18 US disclosed
EP-0958296-A1 NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES DR. REDDY'S RESEARCH FOUNDATION (IN) 1999-11-24 EP disclosed
WO-1997041097-A2 NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES DR. REDDY'S RESEARCH FOUNDATION (IN) 1997-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031759-A1 Novel heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases IAPP, GPR119, CYP11B1 AHR 661/4885TP53 1483/4885HSD11B1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.