Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825663 | 0.83 | HSD17B10 (0.34) | HSD17B10CES2HCAR2 | |
| SCHEMBL17730538 | 0.81 | — | — | |
| SCHEMBL5746753 | 0.75 | ALDH1A1 (0.41) | HSD17B10CES2HCAR2ALDH1A1TDP1 | |
| SCHEMBL4398155 | 0.74 | HSD17B10 (0.39) | HSD17B10CES2HCAR2ALDH1A1TDP1 | |
| SCHEMBL2966833 | 0.72 | — | — | |
| SCHEMBL11294444 | 0.72 | ALDH1A1 (0.31) | HSD17B10ALDH1A1TDP1 | |
| SCHEMBL1298793 | 0.70 | HSD17B10 (0.40) | HSD17B10CES2TDP1 | |
| SCHEMBL1058897 | 0.70 | NAAA (0.41) | HSD17B10CES2HCAR2ALDH1A1TDP1 | |
| SCHEMBL294859 | 0.69 | — | — | |
| SCHEMBL1298067 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | disclosed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | disclosed |