SCHEMBL4453372

SCHEMBL4453372

Clc1cc(Cl)c(-c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSP90AA1 P07900 2/20 0.42
AHR P35869 4/20 0.41
CYP2A6 P11509 1/20 0.41
ESR2 Q92731 2/20 0.39
HTT P42858 2/20 0.39
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PDK2 Q15119 1/20 0.37
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936378 0.85 MEN1 (0.45) CYP3A4MEN1KMT2AHSP90AA1AHR
SCHEMBL4453629 0.81 AHR (0.56) CYP3A4MEN1KMT2AAHRCYP2A6
SCHEMBL15655130 0.81 CYP1A2 (0.50) CYP3A4MEN1KMT2AHSP90AA1AHR
SCHEMBL29995337 0.80 HTT (0.50) CYP3A4MEN1KMT2AHSP90AA1ESR2
SCHEMBL4450643 0.80 ALOX5 (0.42) CYP3A4AHRESR2ALDH1A1TSHR
SCHEMBL10942411 0.80 HPGD (0.52) CYP3A4MEN1KMT2AHSP90AA1AHR
SCHEMBL15655133 0.79 LMNA (0.50) MEN1KMT2ACYP2A6ESR2HTT
SCHEMBL23827190 0.77 AHR (0.67) CYP3A4HSP90AA1AHRALDH1A1HPGD
SCHEMBL2932603 0.77 AHR (0.52) CYP3A4MEN1KMT2AAHRCYP2A6
SCHEMBL24511038 0.76 LMNA (0.48) MEN1KMT2ACYP2A6ESR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-119454328-A Hot compress device for nursing arm pain 西安交通大学医学院第一附属医院 2025-02-18 CN disclosed
CN-118741857-A PCB assembly applied to voltage regulator module and manufacturing method of voltage regulator 台达电子工业股份有限公司 2024-10-01 CN disclosed
CN-117473576-A Supply chain management system based on intelligent cloud platform 福建霖荣供应链管理有限公司 2024-01-30 CN disclosed
CN-116325510-A Steering wheel mounted display assembly maintaining upright orientation regardless of rotational position 库斯特北美公司 2023-06-23 CN disclosed
CN-116234161-A Circuit board and computing device 超聚变数字技术有限公司 2023-06-06 CN disclosed
CN-218976396-U Dual-channel heat dissipation wireless charger 上海金脉电子科技有限公司 2023-05-05 CN disclosed
CN-116057690-A High density optical/electrical interconnect arrangement with high thermal efficiency 艾尤纳公司 2023-05-02 CN disclosed
WO-2023273818-A1 COUPLER AND ELECTRONIC DEVICE 华为技术有限公司 2023-01-05 WO disclosed
CN-217611666-U Charcoal-burning hand warmer 杭州热浪工业设计有限公司 2022-10-21 CN disclosed
CN-217149647-U Multifunctional airing device 灵山县匠星玩具有限公司 2022-08-09 CN disclosed
CN-110345242-B Shift lever apparatus for electronic clutch 现代自动车株式会社 2022-07-29 CN disclosed
CN-113497326-B Coupler, radio frequency circuit board, radio frequency amplifier and electronic equipment 华为技术有限公司 2022-06-10 CN disclosed
CN-112448542-B Electric assembly 比亚迪股份有限公司 2022-02-08 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
WO-1998052648-A1 METHOD FOR DECHLORINATING POLYCHLORINATED BIPHENYLS AND GRANULES FOR USE IN METHOD MICHIGAN BIOTECHNOLOGY INSTITUTE (US) 1998-11-26 WO disclosed
US-5635393-A CULTURING ANAEROBIC METHANOGENIC DECHLORINATING MICROORGANISMS IN NUTRIENT SLUDGES UNTIL GRANULES FORM BHATNAGAR LAKSHMI (US) 1997-06-03 US disclosed