Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | OGG1 | O15527 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822591 | 0.85 | L3MBTL1 (0.56) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3186035 | 0.83 | PARP1 (0.56) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16955875 | 0.80 | C1S (0.50) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16962176 | 0.79 | C1S (0.48) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30277354 | 0.78 | PARP1 (0.63) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3169 | 0.78 | PARP1 (0.63) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL749086 | 0.78 | C1S (0.56) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16952703 | 0.77 | C1S (0.47) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16960675 | 0.77 | L3MBTL1 (0.50) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1814265 | 0.76 | SMN1; SMN2 (0.56) | L3MBTL1PARP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134617-A1 | AMINODIHYDROTHIAZINE DERIVATIVES AS BACE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2009-11-05 | — | — | WO | disclosed |