Styrene

Styrene

SCHEMBL4453476

C=Cc1ccccc1.CCCCOC(=O)CC=CC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.43
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTT P42858 1/20 0.40
BCHE P06276 4/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
APP P05067 1/20 0.40
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
ACHE P22303 2/20 0.39
AKR1C3 P42330 1/20 0.39
HPGD P15428 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL313118 0.86 KDM4E (0.42) HCAR2TSHRTDP1L3MBTL1MEN1
Styrene SCHEMBL8918818 0.84 TDP1 (0.40) TSHRTDP1L3MBTL1MEN1KMT2A
SCHEMBL27998553 0.83 HCAR2 (0.59) HCAR2TSHRALDH1A1MAPTHPGD
Butyl Fumarate SCHEMBL2164919 0.83 HCAR2 (0.67) HCAR2TSHRTDP1L3MBTL1ALDH1A1
Butyl Fumarate SCHEMBL2164913 0.83 HCAR2 (0.67) HCAR2TSHRTDP1L3MBTL1ALDH1A1
Styrene SCHEMBL19582218 0.82 ALDH1A1 (0.43) HCAR2TSHRL3MBTL1ALDH1A1KDM4E
Styrene SCHEMBL5698364 0.82 TSHR (0.59) HCAR2TSHRTDP1L3MBTL1ALDH1A1
Styrene SCHEMBL5698366 0.82 TSHR (0.59) HCAR2TSHRTDP1L3MBTL1ALDH1A1
Styrene SCHEMBL11162678 0.81 ATM (0.61) HCAR2TSHRTDP1L3MBTL1ALDH1A1
Styrene SCHEMBL10459189 0.81 ATM (0.61) HCAR2TSHRTDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8714680-B2 Inkjet recording apparatus and inkjet recording method CANON KABUSHIKI KAISHA (JP) 2014-05-06 US disclosed
US-20120249678-A1 INKJET RECORDING APPARATUS AND INKJET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2012-10-04 US disclosed
US-8215740-B2 Inkjet recording apparatus and inkjet recording method CANON KABUSHIKI KAISHA (JP) 2012-07-10 US disclosed
US-20090315935-A1 INKJET RECORDING APPARATUS AND INKJET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2009-12-24 US disclosed