SCHEMBL4453514

SCHEMBL4453514

CCOCCOC(=O)C(C)=O

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.69
ALDH1A1 P00352 7/20 0.67
TSHR P16473 5/20 0.67
HSD17B10 Q99714 4/20 0.40
LMNA P02545 1/20 0.40
GLO1 Q04760 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16781817 0.92 ALDH1A1 (0.76) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL18214425 0.87 THRB (0.52) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL10766089 0.87 THRB (0.71) THRBALDH1A1TSHRHSD17B10LMNA
Ethyl Pyruvate SCHEMBL14353007 0.87 ALDH1A1 (0.76) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL4676247 0.86 THRB (0.69) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL12088001 0.84 THRB (0.46) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL5408269 0.83 THRB (0.71) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL36524 0.82 THRB (1.00) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL28140750 0.82 THRB (0.44) THRBALDH1A1TSHRHSD17B10LMNA
SCHEMBL2176180 0.81 THRB (0.63) THRBALDH1A1TSHRHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815946-B2 Inhibition of proliferation and fibrotic response of activated corneal stromal cells University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2014-08-26 US claimed
US-20090239947-A1 Inhibition of proliferation and fibrotic response of activated corneal stromal cells UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2009-09-24 US claimed
CN-104583866-B Resin combination, resist film, pattern forming method, the method for manufacturing electronic device, electronic device and compound 富士胶片株式会社 2018-10-02 CN disclosed
US-9500951-B2 Actinic ray-sensitive or radiation-sensitive composition, resist film using the same, pattern forming method, method for manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2016-11-22 US disclosed
US-9459531-B2 2016-10-04 US disclosed
US-9188865-B2 Actinic ray-sensitive or radiation-sensitive composition, resist film using the same, pattern forming method, method for manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2015-11-17 US disclosed
US-20150293446-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-15 US disclosed
US-20150284492-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-08 US disclosed
CN-104583866-A Actinic ray-sensitive or radiation-sensitive resin composition, resist film using the same, pattern forming method, and method for manufacturing electronic device and electronic device, and compound FUJIFILM CORP 2015-04-29 CN disclosed
US-20150010857-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-01-08 US disclosed
US-8815946-B2 Inhibition of proliferation and fibrotic response of activated corneal stromal cells University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2014-08-26 US disclosed
WO-2014034533-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE AND ELECTRONIC DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-03-06 WO disclosed
WO-2013141395-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2013-09-26 WO disclosed
US-20090239947-A1 Inhibition of proliferation and fibrotic response of activated corneal stromal cells UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2009-09-24 US disclosed
US-7230062-B2 Acrylic copolymer KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2007-06-12 US disclosed
US-20050182224-A1 Acrylic copolymer KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2005-08-18 US disclosed