SCHEMBL4453544

SCHEMBL4453544

CCCCC(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.47
CNR2 P34972 1/20 0.41
ALOX5 P09917 2/20 0.41
PPARG P37231 2/20 0.41
PPARA Q07869 1/20 0.41
SLC6A4 P31645 2/20 0.41
PTGES O14684 1/20 0.39
MLNR O43193 1/20 0.39
NR1I2 O75469 1/20 0.39
ESR1 P03372 1/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
ADRB2 P07550 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRB1 P08588 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD2 P14416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445054 0.94 LTA4H (0.47) LTA4HCNR2SLC6A4MLNRNR1I2
SCHEMBL8032386 0.92 CSNK1E (0.46) LTA4HCNR2SLC6A4MLNRNR1I2
SCHEMBL21075852 0.90 LTA4H (0.43) LTA4HCNR2ALOX5PPARGPPARA
Hydrochloric Acid SCHEMBL25265807 0.87 LTA4H (0.41) LTA4HCNR2ALOX5PPARGPPARA
Bromide SCHEMBL25221846 0.87 LTA4H (0.41) LTA4HCNR2ALOX5PPARGPPARA
SCHEMBL6463009 0.87 SLC6A4 (0.43) LTA4HPPARGPPARASLC6A4ALDH1A1
SCHEMBL18473613 0.85 SLC7A5 (0.56) LTA4HALOX5PPARGPPARAGPR88
SCHEMBL27225882 0.83 LTA4H (0.47) LTA4HCNR2ALOX5PPARGPPARA
SCHEMBL10389318 0.83 PPARA (0.41) LTA4HCNR2PPARGPPARACNR1
SCHEMBL28833769 0.83 CNR2 (0.43) CNR2ALOX5PPARGPPARAPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094737-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2009-09-02 EP claimed
WO-2008061662-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2008-05-29 WO claimed
CN-117651750-A Ultraviolet absorber, method for producing same, composition, molded article, and coating film 东洋油墨SC控股株式会社 2024-03-05 CN disclosed
CN-114846085-B Resin composition and molded article 东洋油墨SC控股株式会社 2023-09-08 CN disclosed
EP-2094737-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2009-09-02 EP disclosed
WO-2008061662-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2008-05-29 WO disclosed
US-5084480-A Treatment of pneumonia in persons with AIDS FUJISAWA USA, INC. (US) 1992-01-28 US disclosed
EP-0315467-A2 Pentamidine salts useful in the treatment and prophylaxis of pneumocystis carinii pneumonia LyphoMed, Inc. (US) 1989-05-10 EP disclosed