Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3583791 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL13712183 | 0.82 | HTT (0.40) | LMNACYP19A1RXFP1ALPLKMT2A | |
| SCHEMBL28711155 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL13031253 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL13031308 | 0.79 | CYP19A1 (0.58) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL3588609 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL15484840 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL13384300 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL3587299 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4ERXFP1ALPLKMT2A | |
| SCHEMBL15724293 | 0.75 | EPHX2 (0.41) | ALDH1A1KDM4EPOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
| US-20090030012-A1 | Pyridine, Pyrimidine and Pyrazine Derivatives as Cxcr3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2009-01-29 | — | — | US | disclosed |
| US-20090030012-A1 | Pyridine, Pyrimidine and Pyrazine Derivatives as Cxcr3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2009-01-29 | — | — | US | disclosed |
| EP-1988900-A2 | PYRIDINE, PYRIMIDINE AND PYRAZINE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007100610-A2 | PYRIDINE, PYRIMIDINE AND PYRAZINE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007100610-A2 | PYRIDINE, PYRIMIDINE AND PYRAZINE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-0751424-B1 | Silver halide color photographic material and method for forming image | FUJI PHOTO FILM CO LTD (JP) | 2000-05-31 | — | — | EP | disclosed |
| US-5989789-A | COLOR DEVELOPMENT CARRIED UNDER SPECIFIC DEVELOPING TIMES AND TEMPERATURE; USING A COLOR DEVELOPING SOLUTION WHERE THE SILVER HALIDE SOLVENT IS SELECTED FROM THIOSULFATE, METHANESULFONATE, THIOCYANATE, AND OTHERS OF GIVEN FORMULAS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5985527-A | IMAGES AND DYE DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5882847-A | SUITABLE FOR RAPID PROCESSING; MAGNETIC RECORDING MEDIA | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0751424-A2 | Silver halide color photographic material and method for forming image | FUJI PHOTO FILM CO., LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0726493-A2 | Silver halide color photographic material and image forming method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030012-A1 | Pyridine, Pyrimidine and Pyrazine Derivatives as Cxcr3 Receptor Modulators | CXCR3, CXCR1, CXCR5 | ALDH1A1 1431/4885KDM4E 3976/4885POLB 4082/4885 |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | ALDH1A1 971/4885KDM4E 3447/4885POLB 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.