Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98569 | 0.95 | LMNA (0.42) | LMNACES1CES2ALDH1A1 | |
| SCHEMBL30205788 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL30205659 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL30205784 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL96679 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL97747 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL30205650 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL21049771 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL21049772 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E | |
| SCHEMBL100262 | 0.93 | LMNA (0.45) | LMNACES1CES2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |