Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708424 | 1.00 | TSHR (0.54) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL16735437 | 0.98 | TSHR (0.51) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL16275001 | 0.94 | TSHR (0.54) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL2917316 | 0.94 | TSHR (0.49) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL5836895 | 0.89 | TSHR (0.67) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL9170446 | 0.89 | TSHR (0.67) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL8699776 | 0.89 | TSHR (0.67) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL2041591 | 0.86 | TSHR (0.56) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL16735442 | 0.84 | TSHR (0.45) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL23607552 | 0.84 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377565-A1 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2028208-A1 | Phospholipid copolymers | Tyco Healthcare Group LP (US) | 2009-02-25 | — | — | EP | disclosed |