Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836895 | 1.00 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9170446 | 1.00 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27900968 | 0.93 | TSHR (0.80) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27932128 | 0.93 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23754643 | 0.92 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27883678 | 0.91 | TSHR (0.77) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27788183 | 0.91 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27971664 | 0.91 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5686970 | 0.90 | TSHR (0.74) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5686979 | 0.90 | TSHR (0.74) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800735-A | 1, 3-dioxanes, and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-09-01 | — | — | US | disclosed |