Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170446 | 1.00 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8699776 | 1.00 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27900968 | 0.93 | TSHR (0.80) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27932128 | 0.93 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23754643 | 0.92 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27883678 | 0.91 | TSHR (0.77) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27788183 | 0.91 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27971664 | 0.91 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5686970 | 0.90 | TSHR (0.74) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5686979 | 0.90 | TSHR (0.74) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081280-B2 | Used for electro-optical purposes, and to displays | MERCK PATENT GMBH (DE) | 2006-07-25 | — | — | US | disclosed |
| US-7033654-B2 | mixture of polar compounds of positive dielectric anisotropy in matrix liquid-crystal displays; broad nematic phases, low birefringence, very high specific resistance, good UV and temperature stability and low vapor pressure | MERCK PATENT GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| US-7026020-B2 | Mixture of polar compounds; positive dielectric anisotropy; electrooptic display | MERCK PATENT GMBH (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6953610-B2 | A mixture of halogenated cyclohexylene compounds, positive dielectric anisotropy, birefringence, chemical and heat resistance, low viscosity, stability to electromagnetic radiation, low voltages and high contrast; electrooptic displays | MERCK PATENT GMBH (DE) | 2005-10-11 | — | — | US | disclosed |
| US-6951669-B2 | Mixture of crystal structured halogenated compounds and carbocyclic esters, used as displays in electro-optical apparatus | MERCK PATENT GMBH (DE) | 2005-10-04 | — | — | US | disclosed |
| US-20050035329-A1 | for twisted nematic (TN) and supertwisted nematic (STN) liquid-crystal displays having very short response times and good steepnesses and angle dependencies | HECKMEIER MICHAEL (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20050035330-A1 | A mixture of halogenated cyclohexylene compounds, positive dielectric anisotropy, birefringence, chemical and heat resistance, low viscosity, stability to electromagnetic radiation, low voltages and high contrast; electrooptic displays | HECKMEIER MICHAEL (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20050006437-A1 | Liquid-crystalline medium | HECKMEIR MICHAEL (DE) | 2005-01-13 | — | — | US | disclosed |
| US-20040251447-A1 | Mixture of polar compounds; positive dielectric anisotropy; electrooptic display | HECKMEIER MICHAEL (DE) | 2004-12-16 | — | — | US | disclosed |
| US-20040245501-A1 | Mixture of crystal structured halogenated compounds and carbocyclic esters, used as displays in electro-optical apparatus | HECKMEIER MICHAEL (DE) | 2004-12-09 | — | — | US | disclosed |
| US-6793983-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| US-6287648-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISTROPY | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6146719-A | AN ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHATF MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-14 | — | — | US | disclosed |