Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67105 | 1.00 | KIF11 (0.56) | KIF11TSHRLMNATYRHTR1D | |
| SCHEMBL29050790 | 0.84 | RXRB (0.53) | KIF11KDM4E | |
| SCHEMBL21735 | 0.84 | TSHR (0.48) | KIF11TSHRLMNATYRNPC1 | |
| Water SCHEMBL28104416 | 0.84 | TSHR (0.48) | KIF11TSHRLMNATYRNPC1 | |
| SCHEMBL26915 | 0.84 | KIF11 (0.70) | KIF11TSHRLMNATYRHTR1D | |
| SCHEMBL3423876 | 0.84 | KIF11 (0.70) | KIF11TSHRLMNATYRHTR1D | |
| SCHEMBL5823988 | 0.83 | NPC1 (0.60) | KIF11XDHNPC1RAB9AKDM4E | |
| SCHEMBL27420151 | 0.81 | TSHR (0.46) | KIF11TSHRLMNATYRNPC1 | |
| SCHEMBL27389069 | 0.81 | TSHR (0.46) | KIF11TSHRLMNATYRNPC1 | |
| SCHEMBL27497107 | 0.81 | TSHR (0.46) | KIF11TSHRLMNATYRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703802-A | Boron-containing organic compound and application thereof | 北京鼎材科技有限公司 | 2023-02-17 | — | — | CN | claimed |
| EP-3606971-B1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL IP AMERICA INC (US) | 2022-01-12 | — | — | EP | claimed |
| US-20200181359-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL IP AMERICA INC (US) | 2020-06-11 | — | — | US | claimed |
| US-10597511-B2 | Reactive flame retardant blends for flexible polyurethane foam | ICL-IP AMERICA INC. (US) | 2020-03-24 | — | — | US | claimed |
| EP-3606971-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP America Inc. (US) | 2020-02-12 | — | — | EP | claimed |
| WO-2019060035-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP AMERICA INC. (US) | 2019-03-28 | — | — | WO | claimed |
| US-20190085151-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP AMERICA INC. | 2019-03-21 | — | — | US | claimed |
| EP-2786985-B1 | Antagonists of the glucagon receptor | METABASIS THERAPEUTICS INC (US) | 2018-11-28 | — | — | EP | claimed |
| WO-2017078927-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-05-11 | — | — | WO | claimed |
| EP-3116851-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | Salk Institute for Biological Studies (US) | 2017-01-18 | — | — | EP | claimed |
| US-7026346-B2 | Compounds and methods for inducing apoptosis in proliferating cells | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-04-11 | — | — | US | claimed |
| EP-1499597-A4 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | UNIV OHIO STATE RES FOUND (US) | 2006-01-25 | — | — | EP | claimed |
| EP-1546089-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TransTech Pharma Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2005044130-A1 | PDK-1/AKT SIGNALING INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-05-19 | — | — | WO | claimed |
| EP-1499597-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-01-26 | — | — | EP | claimed |
| EP-1153099-B1 | COMPRESSION HEAT TRANSFER SYSTEM COMPRISING HYDROFLUOROCARBON (HFC) REFRIGERANTS | LUBRIZOL CORP (US) | 2004-09-29 | — | — | EP | claimed |
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TRANSTECH PHARMA, LLC | 2004-06-10 | — | — | US | claimed |
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | claimed |
| US-20030236294-A1 | Compounds and methods for inducing apoptosis in proliferating cells | NIH - DEITR | 2003-12-25 | — | — | US | claimed |
| WO-2003086287-A2 | COMPOUNDS AND METHODS FOR INDUCING APOPTOSIS IN PROLIFERATING CELLS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-10-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TFPI, F9, TFPI2 | KIF11 3454/4885TSHR 478/4885LMNA 75/4885 |
| US-20030236294-A1 | Compounds and methods for inducing apoptosis in proliferating cells | MCL1, BRDT, BAD | KIF11 1623/4885TSHR 3239/4885LMNA 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.