Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454078 | 1.00 | TSHR (0.35) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL9306774 | 0.84 | FFAR3 (0.38) | FFAR3LCKFYN | |
| SCHEMBL8081158 | 0.84 | FFAR3 (0.38) | FFAR3LCKFYN | |
| SCHEMBL1430512 | 0.73 | — | — | |
| SCHEMBL10942185 | 0.71 | CA1 (0.36) | TSHRFFAR3LCKFYN | |
| SCHEMBL713652 | 0.71 | CA1 (0.36) | TSHRFFAR3LCKFYN | |
| SCHEMBL713653 | 0.71 | CA1 (0.36) | TSHRFFAR3LCKFYN | |
| SCHEMBL4119300 | 0.69 | TSHR (0.43) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL819602 | 0.69 | TSHR (0.43) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL9871980 | 0.69 | TSHR (0.43) | TSHRTHPOFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | BIOSIGNAL LIMITED (AU) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048461-A1 | Regulators of Bacterial Signalling Pathways | MRPL21, FNTB, ATF1 | TSHR 1720/4885THPO 4121/4885FFAR3 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.