Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | FABP3 | P05413 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL443146 | 1.00 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 | |
| Dodecanoate SCHEMBL4448269 | 1.00 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 | |
| Adipic Acid SCHEMBL674486 | 0.89 | HDAC1 (0.55) | CES2CES1PPARGCA1 | |
| SCHEMBL384530 | 0.87 | CES2 (0.51) | CES2CES1EPHX2 | |
| SCHEMBL384532 | 0.87 | CES2 (0.51) | CES2CES1EPHX2 | |
| SCHEMBL674807 | 0.86 | CES2 (0.41) | CES2CES1FABP3PPARGCA1 | |
| Stearic Acid SCHEMBL109141 | 0.83 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 | |
| Decanoic Acid SCHEMBL109283 | 0.83 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 | |
| Dodecanoate SCHEMBL4587316 | 0.83 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 | |
| Heptanoate SCHEMBL107320 | 0.83 | CES2 (0.54) | CES2CES1FABP3PPARGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761733-B1 | Rubber compositions and pneumatic tires using the same | BRIDGESTONE CORP (JP) | 2007-05-09 | — | — | EP | claimed |
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| WO-2022124058-A1 | POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE | 株式会社ブリヂストン | 2022-06-16 | — | — | WO | disclosed |
| EP-1958980-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORP (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20090270525-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1958980-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |
| EP-0761733-B1 | Rubber compositions and pneumatic tires using the same | BRIDGESTONE CORP (JP) | 2007-05-09 | — | — | EP | disclosed |
| US-5726237-A | COMPOSITION OF A RUBBER AND CARBON BLACK HAVING LOW ROLLING RESISTANCE AND WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0761733-A2 | Rubber compositions and pneumatic tires using the same | Bridgestone Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |