Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449069 | 0.85 | EDNRA (0.51) | EDNRAUSP30CCR8NSD2KMT2A | |
| SCHEMBL4443344 | 0.83 | LMNA (0.55) | EDNRAUSP30LMNATSHRSMN1; SMN2 | |
| SCHEMBL4448161 | 0.82 | NPY5R (0.50) | EDNRACCR8KCNA5NSD2KMT2A | |
| SCHEMBL4454360 | 0.81 | NSD2 (0.58) | EDNRAKCNA5NSD2KMT2AMEN1 | |
| SCHEMBL4622884 | 0.81 | NSD2 (0.52) | EDNRACCR8NSD2KMT2A | |
| SCHEMBL4447174 | 0.81 | KDM4E (0.51) | EDNRALMNACCR8NSD2KMT2A | |
| SCHEMBL4448268 | 0.81 | MCL1 (0.55) | EDNRALMNATSHRCCR8NSD2 | |
| SCHEMBL4448820 | 0.81 | EDNRA (0.49) | EDNRAUSP30CCR8NSD2KMT2A | |
| Hydrochloric Acid SCHEMBL4453293 | 0.81 | NSD2 (0.59) | KCNA5NSD2KMT2AMEN1 | |
| SCHEMBL4452477 | 0.80 | MEN1 (0.48) | EDNRALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | disclosed |
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |