Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4453293 | 0.99 | NSD2 (0.59) | NSD2KCNA5MEN1KMT2A | |
| SCHEMBL4443339 | 0.83 | NSD2 (0.67) | NSD2MEN1KMT2A | |
| SCHEMBL4443030 | 0.82 | NSD2 (0.74) | NSD2 | |
| Hydrochloric Acid SCHEMBL4448338 | 0.82 | NSD2 (0.67) | NSD2MEN1KMT2A | |
| SCHEMBL4454357 | 0.81 | EDNRA (0.46) | NSD2KCNA5MEN1KMT2AEDNRA | |
| SCHEMBL4443335 | 0.81 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444986 | 0.81 | NSD2 (0.74) | NSD2 | |
| Hydrochloric Acid SCHEMBL4446935 | 0.80 | NSD2 (0.78) | NSD2 | |
| SCHEMBL4449107 | 0.79 | NSD2 (0.68) | NSD2 | |
| SCHEMBL4445041 | 0.78 | NSD2 (0.67) | NSD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |