Urea

Urea

SCHEMBL4454525

C=C.NC(N)=O.NC(N)=O

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.75
ALDH1A1 P00352 4/20 0.75
TDP1 Q9NUW8 3/20 0.75
OR51E2 Q9H255 1/20 0.75
ACHE P22303 1/20 0.50
TSHR P16473 3/20 0.46
FGFR4 P22455 1/20 0.46
BLM P54132 4/20 0.46
PMP22 Q01453 3/20 0.46
ALOX15 P16050 2/20 0.46
LDHA P00338 2/20 0.42
LDHB P07195 1/20 0.42
CYP3A4 P08684 3/20 0.39
NFKB1 P19838 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 2/20 0.39
THPO P40225 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL36685 1.00
Urea SCHEMBL687586 1.00
Urea SCHEMBL3460099 1.00 LMNA (0.75) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL27296627 0.94 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL4966254 0.94
Urea SCHEMBL9346736 0.94
Urea SCHEMBL3459680 0.94 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL20528004 0.94 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL14631360 0.94
Urea SCHEMBL28098547 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108348986-B Casting mold molding kit 花王株式会社 2020-08-28 CN claimed
WO-2009091350-A1 POLYCARBAMIDES, POLYCARBAMATES, AND POLYCARBAMIDE-FORMALDEHYDE AND POLYCARBAMATE-FORMALDEHYDE CONDENSATION RESINS MISSISSIPPI STATE UNIVERSITY (US) 2009-07-23 WO claimed
US-20090149608-A1 Polycarbamides, polycarbamates, and polycarbamide-formaldehyde and polycarbamate-formaldehyde condensation resins MISSISSIPPI STATE UNIVERSITY 2009-06-11 US claimed
CN-112512722-B Binder composition for mold making 花王株式会社 2023-02-28 CN disclosed
CN-112512722-A Binder composition for mold making 花王株式会社 2021-03-16 CN disclosed
CN-112368091-A Binder composition for mold making 花王株式会社 2021-02-12 CN disclosed
CN-112236247-A Binder composition for mold making 花王株式会社 2021-01-15 CN disclosed
CN-112203784-A Binder composition for mold making 花王株式会社 2021-01-08 CN disclosed
CN-108348986-B Casting mold molding kit 花王株式会社 2020-08-28 CN disclosed
WO-2009091350-A1 POLYCARBAMIDES, POLYCARBAMATES, AND POLYCARBAMIDE-FORMALDEHYDE AND POLYCARBAMATE-FORMALDEHYDE CONDENSATION RESINS MISSISSIPPI STATE UNIVERSITY (US) 2009-07-23 WO disclosed
US-20090149608-A1 Polycarbamides, polycarbamates, and polycarbamide-formaldehyde and polycarbamate-formaldehyde condensation resins MISSISSIPPI STATE UNIVERSITY 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149608-A1 Polycarbamides, polycarbamates, and polycarbamide-formaldehyde and polycarbamate-formaldehyde condensation resins SUV39H1, PFAS, SUV39H2 LMNA 953/4885ALDH1A1 2009/4885TDP1 1835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.