Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MPO | P05164 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | CTSC | P53634 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 1/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064069 | 0.88 | MMP9 (0.68) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL29924850 | 0.86 | KDM4E (0.65) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL5583839 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL9596908 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL29701966 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL11855463 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL9596897 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL5612810 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL3359705 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL9869824 | 0.85 | ACE (0.72) | MAPTKDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819000-B1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2009-07-08 | — | — | EP | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |