SCHEMBL4454635

SCHEMBL4454635

CC(=O)O[SiH]1C[Si](C)(OC(C)=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33525104 0.71 ALDH1A1 (0.35)
SCHEMBL33525138 0.68 ALDH1A1 (0.37)
SCHEMBL9184653 0.67
SCHEMBL20942803 0.67 HSD17B10 (0.32)
SCHEMBL20942791 0.65 HSD17B10 (0.31)
SCHEMBL28225125 0.62 ALDH1A1 (0.32)
SCHEMBL4456584 0.57 ALDH1A1 (0.37)
SCHEMBL13714789 0.56 ALDH1A1 (0.35)
SCHEMBL13714810 0.56 ALDH1A1 (0.35)
SCHEMBL9181709 0.54 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9061317-B2 Porogens, porogenated precursors and methods for using the same to provide porous organosilica glass films with low dielectric constants AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-06-23 US disclosed
US-8951342-B2 Methods for using porogens for low k porous organosilica glass films AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-02-10 US disclosed
US-20130095255-A1 Porogens, Porogenated Precursors and Methods for Using the Same to Provide Porous Organosilica Glass Films with Low Dielectric Constants AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-04-18 US disclosed
US-20120282415-A1 Methods For Using Porogens For Low K Porous Organosilica Glass Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-11-08 US disclosed
EP-2116632-A2 Porogens, porogenated precursors and methods for using the same to provide porous organosilica glass films with low dielectric constants Air Products and Chemicals, Inc. (US) 2009-11-11 EP disclosed
US-20080268177-A1 Porogens, Porogenated Precursors and Methods for Using the Same to Provide Porous Organosilica Glass Films with Low Dielectric Constants AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-10-30 US disclosed