SCHEMBL4454689

SCHEMBL4454689

COP(=O)(OC)C(O)CO

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
CYP2C19 P33261 1/20 0.44
FDPS P14324 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452186 0.80 LMNA (0.41) LMNACYP2C19FDPSPPARD
SCHEMBL10952581 0.79 LMNA (0.44) LMNACYP2C19FDPSPPARD
SCHEMBL1053552 0.77 LMNA (0.43) LMNACYP2C19FDPS
SCHEMBL4453650 0.77 LMNA (0.39) LMNACYP2C19PPARD
SCHEMBL19018509 0.75 CTSA (0.39) CYP2C19TDP1
SCHEMBL5897538 0.75 LMNA (0.41) LMNACYP2C19FDPS
SCHEMBL14438178 0.73 LMNA (0.40) LMNACYP2C19FDPS
SCHEMBL10831670 0.71 LMNA (0.52) LMNACYP2C19FDPS
SCHEMBL3806259 0.71
Trichlorfon SCHEMBL4750566 0.70 LMNA (0.83) LMNACYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed